Skip to main content

Evaluate fatigue in your workplace

Fatigue Biomarker Testing

Almost all organizations understand that fatigue in the workforce is troublesome. Missed work, accidents, poor performance, and high turnover all come with considerable costs. Notably, fatigue is also associated with increased healthcare expenditures. You want to get ahead of the problem, but how can you tackle such a big and complicated issue?

The key is objectively measuring fatigue in your workforce. With accurate data on how fatigued people are, you can gain a deeper understanding of where fatigue is occurring in your organization and help your employees get the care they may need to live fuller and more productive lives. With this information, making management decisions that keep fatigue at a lower level is now possible.


Fatigue is normal. Everybody experiences it occasionally–it’s an important signal that tells us to slow down and recover. However, some people may suffer from a persistent fatigue issue. The underlying cause of prolonged high levels of fatigue could be related to physiologic issues that make high quality sleep difficult to obtain. Long commutes and lifestyle can reduce rest too. If someone is struggling consistently with fatigue, there may be a solution at hand that can reduce or eliminate fatigue. Having the tools to identify solutions to fatigue helps organizations to save on costs, retain high quality employees, and improve their quality of life.

A photo of a nurse that experiences exhaustion and fatigue because of her demanding work schedule.


Fatigue biomarker testing has its roots in U.S. military research that was initially focused on understanding the effects of fatigue among the ranks of the Army. Hyperion’s own Dr. John Kalns proposed a research study that sought to identify key biomarkers of fatigue from a saliva sample. The study evaluated molecular entities that emerged after subjects performed long periods of endurance training. The result was groundbreaking – for the first time, a pair of novel peptides were found to change significantly in concentration following physical exertion and thus could be utilized as objective measures of fatigue. This incredible finding serves as the foundation for the testing services that we provide today.


Uncovering the effects of fatigue in your organization has never been easier. From a series of non-invasive saliva samples and some additional information on employees’ health and working habits, we can efficiently and accurately determine how fatigue may be affecting your workforce and healthcare expenditures. 

If you have questions about the process or you’re wondering how this service can benefit your organization, contact us today. We are happy to discuss the details and formulate a plan that best serves your needs.


Our testing procedures are rooted in the latest scientific literature, and we strive to promote further fatigue biomarker research. In partnership with respected collaborators, we have made significant strides in this field. By upholding rigorous standards of scientific integrity, we are always improving.


Hyperion Biotechnology is a Woman-Owned, Service-Disabled, Veteran-Owned small business currently doing business in more than 20 states. Our laboratory in San Antonio, TX, is fully licensed and complies with all state and federal requirements, and has been CLIA certified for more than 10 years, ensuring consistent high quality. We have worked with a number of professional and athletic organizations to bring them the information they need to make better decisions about how they work, rest, and train. Our mission is to empower individuals and organizations by providing services that improve lives.


Fatigue biomarker testing is likely new to you. ‘New’ doesn’t have to mean confusing. If you still have questions, we are all ears.


Hyperion Biotechnology has developed and determined the performance characteristics of its human performance and fatigue assays. These in-house assays have not been cleared or approved by the U.S. Food and Drug Administration (“FDA”) and are considered for investigational and research purposes only. Hyperion Biotechnology makes no claims as to the diagnostic or therapeutic use of its tests or other informational materials. Hyperion Biotechnology is not responsible or liable for misuse or misinterpretation of the information provided, or any diagnoses or healthcare changes initiated by a patient, or a healthcare practitioner based on the content of Hyperion Biotechnology’s informational materials. Tests meet validated performance specifications as required by Clinical Laboratory Improvement Amendment of 1988 (CLIA) though they are not intended for any clinical decision-making purposes of any kind.