Publications and Patents

Michael DJ, Daugherty S, Santos A, Ruby BC, Kalns JK, (In press), Fatigue biomarker index: An objective salivary measure of fatigue level, Accident Analysis and Prevention.

Oakley J, Prahl J, Daheshia M, Price G, Boswell G, Alexander S, 2013, Diagnosis of right ventricular cardiac sarcoidosis with cardiac magnetic resonance in a patient presenting with ventricular tachycardia, Mil Med 178, 2:e265.

Seda G, Stafford C, Parrish J, Praske S, Daheshia M, 2012, Population characterization, histological evaluation, and timeliness of care of surgical nonsmall cell lung cancer patients in a military academic medical center, Mil Med, 177, 6:748.

Shandley S, Prato Matthews K, Cox J, Romano D, Abplanalp A, Kalns J, 2012, Efficacy of hyperbaric oxygen therapy in a mouse model of implant-associated osteomyelitis, J Orthop Res, 30(2):203-8.

Suliman HS, Fecura SE, Baskin J, Kalns JE, 2011, Laboratory evaluation of 10 heat and moisture exchangers using simulated aeromedical evacuation conditions, Mil Med 176(6):656-9.

Kalns J, Cox J, Baskin J, Santos A, Odland R, Fecura Jr S, 2011, Extremity compartment syndrome in pigs during hypobaric simulation of aeromedical evacuation, Aviat Space Environ Md 82(2):87-91.

Kalns J, Cox J, Baskin J, Santos A, Odland R, Fecura Jr S, 2011, Threshold model for extremity compartment syndrome in swine, J Surg Res 167(1):e13-9.

Fogt DL, Cooke WH, Kalns JK, Michael DJ, 2011, Linear mixed-effects modeling of relationship between heart rate variability and fatigue arising from sleep deprivation, Aviation, Space and Environmental Medicine 82:1104-1109.

Kalns J, Baskin J, Reinert A, Michael DJ, Santos A, Daugherty S, Wright J, 2011, Predicting success in the Tactical Air Combat Party (TACP) training pipeline, Mil Med 176:431-7.

Fogt DL, Kalns JE, Michael D, 2010, A comparison of cognitive performance decreases during acute, progressive fatigue arising from different concurrent stressors, Mil Med 175:939-44.

Shandley S, Prato Matthews K, Cox J, Romano D, Abplanalp A, Kalns J, Michaelson, R, Efficacy of Hyperbaric Oxygen Therapy in a Mouse Model of Implant-Associated Osteomyelitis, poster presented at 2010 Undersea and Hyperbaric Medicine Society annual meeting, June, St. Petersburg, FL.

Cox JM, Kalns JE, 2010, Development and characterization of a rat model of nonpenetrating liver trauma, Comp Med. 60(3):218-24.

Imoukhuede PI, Moss FJ, Michael DJ, Chow RH, Lester HA, 2009, Ezrin mediates tethering of the ?-aminobutyric acid transporter GAT1 to actin filaments via a C-terminal PDZ-interacting domain, Biophys J 96:1-12.

Michael DJ, Tapechum S, Rohan JG, Johnson JM, Chow RH, 2009, Fluorescent cargo proteins in peptidergic endocrine cells: cell type determines secretion kinetics at exocytosis, Ann NY Acad Sci 1152:7-17.

Shandley S, Martinez S, Krolick, K, 2009, IL-4 receptor as a bridge between the immune system and muscle in experimental myasthenia gravis I: Up-regulation of muscle IL-15 by IL-4, Clin Immunol 132(2):246-56.

Fogt DL, Brosch LC, Dacey DC, Kalns JE, Ketchum NS, Rohrbeck P, Venuto MM, Tchandja JB, Bunning ML, 2009, Hydration status of Air Force military basic trainees after implementation of the back-mounted hydration system, Mil Med 174(8):821-7.

Fogt DL, Cooper PJ, Freeman CN, Kalns JE, Cooke WH, 2009, Heart rate variability to assess combat readiness, Mil Med 174(5):491-5.

Wright JK, Christy RJ, Tharp RV, Kalns JE, 2009, Evaluation of intraosseous delivery of factor VIIa during hemorraghic shock in the pig, Mil Med 174(2):119-23.

Kiel JL, Parker JE, Holwitt EA, McCreary RP, Andrews CJ, De Los Santos A, Wade M, Kalns J, Walker W, 2008, Geographical distribution of genotypic and phenotypic markers among Bacillus anthracis isolates and related species by historical movement and horizontal transfer, Folia Microbiol 53(6):472-8.

Michael DJ, Xiong W, Geng X, Drain P, Chow RH, 2007, Human insulin vesicle dynamics during pulsatile secretion, Diabetes 56: 1277-1288.

Oubre CM, Roy A, Toner C, Kalns JE, 2007, Retrospective study of factors affecting non-healing of wounds during hyperbaric oxygen therapy, J Wound Care 16(6):245-50.

Millenbaugh NJ, Kiel JL, Ryan KL, Blystone RV, Kalns JE, Brott BJ, Cerna CZ, Lawrence WS, Soza LL, Mason PA, 2006, Comparison of blood pressure and thermal responses in rats exposed to millimeter wave energy or environmental heat, Shock 25(6):625-32.

Michael DJ, Cai H, Xiong W, Ouyang J, Chow RH, 2006, Mechanisms of peptide hormone secretion, Trend Endocrin Met 17: 408-415.

Oheim M, Michael DJ, Geisbauer M, Madsen D, Chow RH, 2006, Principles of two-photon excitation fluorescence microscopy and other nonlinear imaging approaches, Adv Drug Deliver Rev 58: 788-808.

Michael DJ, Ritzel RA, Haataja L, Chow RH, 2006, Pancreatic beta cells secrete insulin in fast- and slow-release forms, Diabetes 55: 600-607.

Michael DJ, Geng XH, Cawley NX, Loh YP, Rhodes CJ, Drain P, Chow RH, 2004, Fluorescent cargo proteins in pancreatic beta-cells: Design determines secretion kinetics at exocytosis, Biophys J 87: L3-L5.

Wright JK, Kalns J, Wolf EA, Traweek F, Schwarz S, Loeffler CK, Snyder W, Yantis LD Jr, Eggers J, 2004, Thermal injury resulting from application of a granular mineral hemostatic agent, J Trauma 57(2):224-30.

Kalns J, Roy A, Loeffler C, Wright JK, 2004, A retrospective evaluation of digital wound imaging to predict response to hyperbaric oxygen treatment, Ostomy Wound Manage 50(4):36-8, 40, 42 passim.

Kalns JE, Dick EJ Jr, Scruggs JP, Kieswetter K, Wright JK, 2003, Hyperbaric oxygen treatment prevents up-regulation of angiogenesis following partial-thickness skin grafts in the pig, Wound Repair Regen 11(2):139-44.

Venton BJ, Michael DJ, Wightman RM, 2003, Correlation of local changes in extracellular oxygen and pH that accompany dopaminergic terminal activity in the rat caudate-putamen, J Neurochem 84:373-381.

Kalns J, Morris J, Eggers J, Kiel J, 2002, Delayed treatment with doxycycline has limited effect on anthrax infection in BLK57/B6 mice, Biochem Biophys Res Commun 297(3):506-9.

Kalns J, Lane J, Delgado A, Scruggs J, Ayala E, Gutierrez E, Warren D, Niemeyer D, George Wolf E, Bowden RA, 2002, Hyperbaric oxygen exposure temporarily reduces Mac-1 mediated functions of human neutrophils, Immunol Lett 83(2):125-31.

Kalns J, Scruggs J, Millenbaugh N, Vivekananda J, Shealy D, Eggers J, Kiel J, 2002, TNF receptor 1, IL-1 receptor, and iNOS genetic knockout mice are not protected from anthrax infection, Biochem Biophys Res Commun 292(1):41-4.

Gan Y, Mo Y, Kalns JE, Lu J, Danenberg K, Danenberg P, Wientjes MG, Au JL, 2001, Expression of DT-diaphorase and cytochrome P450 reductase correlates with mitomycin C activity in human bladder tumors, Clin Cancer Res 7(5):1313-9.

Travis ER, Wang YM, Michael DJ, Caron MG, Wightman RM, 2000, Differential quantal release of histamine and 5-hydroxytryptamine from mast cells of vesicular monoamine transporter 2 knockout mice, P Natl Acad Sci USA 97:162-167.

Kilpatrick MR, Rooney MB, Michael DJ, Wightman RM, 2000, Extracellular dopamine dynamics in rat caudate-putamen during experimenter-delivered and intracranial self-stimulation, Neuroscience 96:697-706.

Bath BD, Michael DJ, Trafton BJ, Joseph JD, Runnels PL, Wightman RM, 2000, Subsecond adsorption and desorption of dopamine at carbon-fiber microelectrodes, Anal Chem 72:5994-6002.

Kiel JL, Parker JE, Alls JL, Kalns J, Holwitt EA, Stribling LJ, Morales PJ, Bruno JG, 2000, Rapid recovery and identification of anthrax bacteria from the environment, Ann N Y Acad Sci 916:240-52.

Redkar R, Kalns J, Butler W, Krock L, McCleskey F, Salmen A, Piepmeier E Jr, DelVecchio V, 2000, Identification of bacteria from a non-healing diabetic foot wound by 16 S rDNA sequencing, Mol Cell Probes. 14(3):163-9.

Kalns J, Ryan KL, Mason PA, Bruno JG, Gooden R, Kiel JL, 2000, Oxidative stress precedes circulatory failure induced by 35-GHz microwave heating, Shock 13(1):52-9.

Kalns JE, Piepmeier EH, 1999, Exposure to hyperbaric oxygen induces cell cycle perturbation in prostate cancer cells, In Vitro Cell Dev Biol Anim 35(2):98-101.

Piepmeier EH, Kalns JE, 1999, Fibroblast response to rapid decompression and hyperbaric oxygenation, Aviat Space Environ Med 70(6):589-93.

Michael DJ, Wightman RM, 1999, Electrochemical monitoring of biogenic amine neurotransmission in real time, J Pharmaceut Biomed 19:33-46.

Michael DJ, Joseph JD, Kilpatrick MR, Travis ER, Wightman R, 1999, Improving data acquisition for fast scan cyclic voltammetry, Anal Chem 71:3941-3947.

Garris PA, Kilpatrick M, Bunin MA, Michael DJ, Walker QD and Wightman RM, 1999, Dissociation of dopamine release in the nucleus accumbens from intracranial self-stimulation, Nature 398:67-69.

Michael DJ, Travis ER, Wightman RM, 1998, Color images for fast-scan cyclic voltammetry, Anal Chem 70:586A-592A.

Kalns J, Parker J, Bruno J, Holwitt E, Piepmeier E, Kiel J, 1998, Nitrate reductase alters 3-nitrotyrosine accumulation and cell cycle progression in LPS + IFN-gamma-stimulated RAW 264.7 cells, Nitric Oxide 2(5):366-74.

Bruno JG, Parker JE, Kalns J, Darcy TJ, Grubbs TR, Cox AB, Morales PJ, Alls JL, Kiel JL, 1998, Characterization of NR10(2) macrophages, In Vitro Cell Dev Biol Anim 34(8):613-6.

Kalns J, Krock L, Piepmeier Jr E, 1998, The effect of hyperbaric oxygen on growth and chemosensitivity of metastatic prostate cancer, Anticancer Res 18(1A):363-7.

Piepmeier EH, Kalns JE, McIntyre KM, Lewis ML, 1997, Prolonged weightlessness affects promyelocytic multidrug resistance, Exp Cell Res 237(2):410-8.

Au JL, Kalns J, Gan Y, Wientjes MG., 1997, Pharmacologic effects of paclitaxel in human bladder tumors, Cancer Chemother Pharmacol 41(1):69-74

Wightman RM, Hochstetler S, Michael DJ, Travis E, 1996, Chemical communication: using microelectrodes as secretion probes in biological systems, Interface 5:22-26.

Kalns JE, Millenbaugh NJ, Wientjes MG, Au JL, 1995, Design and analysis of in vitro antitumor pharmacodynamic studies, Cancer Res 55(22):5315-22.


Kalns John E and Michael Darren. 2013. Methods and Compositions for Biomarkers of Fatigue, Fitness and Physical Performance Capacity. U.S. Patent No. 8,442,808. Filed 9/11/2009, issued 5/14/2013.

Fogt Donovan, Kalns John, Michael Darren, and Cooke William. Measurements of Fatigue Level Using Heart Rate Variability Data (Under Review) Application Number: PCT/US2011/032536; Filed 04/14/2011.

Kalns John and Michael Darren. Methods and Compositions for Biomarkers of Fatigue (Under Review) Application Number: US 61/559,632; Filed 11/14/2011.