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Fatigue Biomarker Research

Hyperion is interested in new ways to use its technology to solve problems.

Awards will include free testing and cash payments of up to $2,500.   Please complete a white paper that clearly describes your hypothesis, how the project will be completed, and how data will be used.  If proposals involve human subjects research, the study must be reviewed by an independent Investigational Review Board (IRB).  We strongly encourage academic investigators with current approved or pending protocols to engage with us so we can support your current research efforts. 

Areas of high interest include:

  • Use of fatigue biomarker in the workplace. Identification and measurement of fatigue may reduce the frequency of accidents, mistakes, and lead to changes in how work is managed and organized.
  • Use of fatigue biomarker to measure effectiveness of drugs, supplements and diet.  The relationship between fatigue biomarker expression and diet, obesity and diabetes are of high interest.   
  • Effect of fatigue biomarker peptides on gut microbiome.  Fatigue peptides are thought to interact with gut microbiome, and many have effects on the immune system.  Investigators with robust murine models of human disease are encouraged to contact us.  
  • Performance optimization strategies using human performance biomarkers as a feedback and monitoring system.  
  • Oral fluid-based detection of naltrexone and metabolite to evaluate compliance with the Sinclair Method.

Ongoing Research Programs

Hyperion is active with several investigators exploring use of fatigue biomarker for diagnosis of ME/CFS, long-COVID and other diseases where fatigue is an important clinical feature.   If you are a patient interested in participating in research on ME/CFS or long-COVID please contact SOLVEMECFS.

Publications on fatigue biomarker